Turcan and Fraser introduce the reader to the handbook. It is the first attempt to discuss and advance entrepreneurship field from multi-disciplinary perspectives. The authors invited original contributions from authors, who are experts in their own fields, to provide state-of-the-art insights from their own discipline and explore how these insights might help generate new areas for research, new theories and concepts, and new questions for policy debates—all aimed to advance the entrepreneurship field in the years to come. Turcan and Fraser consider this collection of original chapters in the handbook as a catalyst for an inter-, cross-, and multi-disciplinary dialogue between myriad of perspectives from humanities, social sciences, natural sciences, medical sciences, and technology and production sciences, and entrepreneurship.